Expeditious Synthesis of Ieodoglucomides A and B from the Marine‐Derived Bacterium Bacillus licheniformis

We report the total synthesis of ieodoglucomides A and B. The key steps of the synthesis are a glycosyl‐iodide‐mediated β‐stereoselective glycosylation without neighbouring‐group participation, a regioselective acylation, and a Grubbs cross‐metathesis reaction. The short and efficient synthesis involves 11 steps, with 38–40 % overall yield. The total synthesis of the marine‐derived bacterial glycopeptides ieodoglucomides A and B is reported. The key steps of the synthesis are a glycosyl‐iodide‐mediated β‐stereoselective glycosylation without neighbouring‐group participation, a regioselective acylation, and a Grubbs cross‐metathesis reaction. The synthesis involves 11 steps, with 38–40 % overall yield.