First Gene Cassettes of Integrons as Targets in Finding Adaptive Genes in Metagenomes

The first gene cassettes of integrons are involved in the last adaptation response to changing conditions and are also the most expressed. We propose a rapid method for the selection of clones carrying an integron first gene cassette that is useful for finding adaptive genes in environmental metagen...

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Veröffentlicht in:Applied and Environmental Microbiology 2009-06, Vol.75 (11), p.3823-3825
Hauptverfasser: Huang, Lionel, Cagnon, Christine, Caumette, Pierre, Duran, Robert
Format: Artikel
Sprache:eng
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Zusammenfassung:The first gene cassettes of integrons are involved in the last adaptation response to changing conditions and are also the most expressed. We propose a rapid method for the selection of clones carrying an integron first gene cassette that is useful for finding adaptive genes in environmental metagenomic libraries.
ISSN:0099-2240
1098-5336
1098-6596
DOI:10.1128/AEM.02394-08