Discovery of glpC, an Organic Solvent Tolerance-Related Gene in Escherichia coli, Using Gene Expression Profiles from DNA Microarrays

Gene expression profiles were collected from Escherichia coli strains (OST3410, TK33, and TK31) before and after exposure to organic solvents, and the six genes that showed higher gene expression were selected. Among these genes, glpC encoding the anaerobic glycerol-3-phosphate dehydrogenase subunit...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied and Environmental Microbiology 2005-02, Vol.71 (2), p.1093-1096
Hauptverfasser:	Shimizu, Kazunori, Hayashi, Shuhei, Kako, Takeshi, Suzuki, Maiko, Tsukagoshi, Norihiko, Doukyu, Noriyuki, Kobayashi, Takeshi, Honda, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Biological and medical sciences Cyclohexanes - pharmacology Deoxyribonucleic acid DNA Escherichia coli K12 - drug effects Escherichia coli K12 - genetics Escherichia coli K12 - growth & development Escherichia coli K12 - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Evolutionary and Genomic Microbiology Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Profiling Gene Expression Regulation, Bacterial Genetics Glycerolphosphate Dehydrogenase - genetics Glycerolphosphate Dehydrogenase - metabolism Microbiology Oligonucleotide Array Sequence Analysis - methods Solvents - pharmacology Xylenes - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Gene expression profiles were collected from Escherichia coli strains (OST3410, TK33, and TK31) before and after exposure to organic solvents, and the six genes that showed higher gene expression were selected. Among these genes, glpC encoding the anaerobic glycerol-3-phosphate dehydrogenase subunit C remarkably increased the organic solvent tolerance.
ISSN:	0099-2240 1098-5336
DOI:	10.1128/AEM.71.2.1093-1096.2005