Hypoglycemic and hypolipidemic effects of aqueous extract of Arachis hypogaea in normal and Alloxan-induced diabetic rats

The hypoglycemic and hypolipidemic effect of aqueous extract of Arachis hypogaea was investigated in normal and alloxan-induced diabetic rats. The extract caused a significant (P < 0.05) decrease of fasting blood glucose of both normal and alloxan-induced diabetic rats from 102.60 ± 1.65 mg/dl to...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2002-09, Vol.9 (6), p.553-555
Hauptverfasser:	Bilbis, L.S., Shehu, R.A., Abubakar, M.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	alloxan Animals Arachis Arachis hypogaea Blood Glucose - drug effects Blood Glucose - metabolism cholesterol Cholesterol - blood Cholesterol, HDL - blood Cholesterol, HDL - drug effects Cholesterol, LDL - blood Cholesterol, LDL - drug effects Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - chemically induced Diabetes Mellitus, Experimental - drug therapy diabetics hypoglycemia Hypoglycemic Agents - therapeutic use hypolipidemia Hypolipidemic Agents - therapeutic use Lipids - blood Male Phytotherapy Plant Extracts - therapeutic use Rats triglyceride
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Zusammenfassung:	The hypoglycemic and hypolipidemic effect of aqueous extract of Arachis hypogaea was investigated in normal and alloxan-induced diabetic rats. The extract caused a significant (P < 0.05) decrease of fasting blood glucose of both normal and alloxan-induced diabetic rats from 102.60 ± 1.65 mg/dl to 88.79 ± 0.94 mg/dl for normal and 189.0 ± 30.79 mg/dl to 107.55 ± 1.54 mg/dl for alloxan-induced diabetic rats. The extract also caused a significant (P < 0.05) decrease in serum triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol in both normal and alloxan-induced diabetic rats.
ISSN:	0944-7113 1618-095X
DOI:	10.1078/09447110260573191