DONOR BLOOD FROZEN AND STORED BETWEEN -20°C AND -25°C WITH 35-DAY POST-THAW SHELF LIFE

With standard blood bank facilities and interconnected plastic bags donor erythrocytes can be frozen and stored in commercial freezers at temperatures of -20° to - 25°C for at least 6 months. The cryoprotectant, a mixture of glycerol and dextrose, is washed off in a closed-circuit system. After bein...

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Veröffentlicht in:The Lancet (British edition) 1989-01, Vol.333 (8629), p.71-73
Hauptverfasser: Lovric, V.A., Klarkowski, D.B.
Format: Artikel
Sprache:eng
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Zusammenfassung:With standard blood bank facilities and interconnected plastic bags donor erythrocytes can be frozen and stored in commercial freezers at temperatures of -20° to - 25°C for at least 6 months. The cryoprotectant, a mixture of glycerol and dextrose, is washed off in a closed-circuit system. After being thawed and reconstituted with an additive solution, the pack of red cells can be stored in liquid form for up to 35 days at 4°-6°C. The system lends itself to routine clinical blood transfusion practice.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(89)91429-3