Synthesis and Modification of 6-thiazolyl-4-methylumbelliferone

Synthesis and Modification of 6-thiazolyl-4-methylumbelliferone

6-(2-Methylthiazol-4-yl)-4-methylumbelliferone derivatives were synthesized from 4-(1,3-thiazol-4-yl)-1,3-benzenediols via a Pechmann reaction and were modified by acylation and aminomethylation.

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Veröffentlicht in:Chemistry of natural compounds 2018-05, Vol.54 (3), p.439-442
Hauptverfasser: Shokol, T. V., Abdullaev, E. N., Gorbulenko, N. V., Frasinyuk, M. S., Khilya, V. P.
Format: Artikel
Sprache:eng
Schlagworte:
Acylation
Chemical synthesis
Coumarins
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Zusammenfassung:6-(2-Methylthiazol-4-yl)-4-methylumbelliferone derivatives were synthesized from 4-(1,3-thiazol-4-yl)-1,3-benzenediols via a Pechmann reaction and were modified by acylation and aminomethylation.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-018-2374-3