One-Pot Synthesis of N-Substituted Alkylaminocyclohexanols by the Addition of Electrophiles Formed in situ in the System Н2О2 + HBr (HCl)

One-Pot Synthesis of N-Substituted Alkylaminocyclohexanols by the Addition of Electrophiles Formed in situ in the System Н2О2 + HBr (HCl)

Highly selective one-pot synthesis of N-substituted aminocyclohexanols has been performed by hydroxyhalogenation of the corresponding cyclohexenes with electrophilic reagents formed in situ in the system Н 2 О 2 + HHlg (Hlg = Cl, Br), with subsequent substitution of halogen atoms with amines. Some p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Russian journal of general chemistry 2018-04, Vol.88 (4), p.650-657
Hauptverfasser: Sadygov, O. A., Alimardanov, Kh. M., Ismailova, Sh. I., Babaev, N. R.
Format: Artikel
Sprache:eng
Schlagworte:
Additives
Amines
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Fungicides
Lubricants
Reagents
Substitutes
Synthesis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highly selective one-pot synthesis of N-substituted aminocyclohexanols has been performed by hydroxyhalogenation of the corresponding cyclohexenes with electrophilic reagents formed in situ in the system Н 2 О 2 + HHlg (Hlg = Cl, Br), with subsequent substitution of halogen atoms with amines. Some products were tested as antimicrobial additives to motor oils and cooling lubricants and showed high antibacterial and antifungal activity.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363218040072