One-pot and multi-step syntheses of new 2-(4,5-dihydro-1H-pyrazol-1-yl) thiazole derivatives

One-pot and multi-step syntheses of new 2-(4,5-dihydro-1H-pyrazol-1-yl) thiazole derivatives

β-Ketoester and ethanone derivatives, potentially functional molecules, containing the pyrazole/thiazole scaffolds were synthesized. The structures of the synthesized novel compounds were confirmed by FTIR, 1H NMR and 13C NMR spectroscopy and elemental analysis. The NMR spectra of the synthesized co...

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Veröffentlicht in:Organic communications 2018-04, Vol.11 (2), p.98-110
Hauptverfasser: Gümüş, Mehmet, Dişli, Ali, Yakan, Mehmet, Yiğitcan, Serhat, Koca, İrfan
Format: Artikel
Sprache:eng
Schlagworte:
Chemical synthesis
Coupling (molecular)
Derivatives
Fourier transforms
Magnetic resonance spectroscopy
Molecular chains
NMR spectroscopy
Protons
Pyrazole
Spectrum analysis
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Zusammenfassung:β-Ketoester and ethanone derivatives, potentially functional molecules, containing the pyrazole/thiazole scaffolds were synthesized. The structures of the synthesized novel compounds were confirmed by FTIR, 1H NMR and 13C NMR spectroscopy and elemental analysis. The NMR spectra of the synthesized compounds are analyzed. Furthermore, ABX systems in pyrazole ring were studied in detail and the coupling constants of the diastereotopic protons.
ISSN:1307-6175
1307-6175
DOI:10.25135/acg.oc.40.18.03.071