A Review: Solanum nigrum L. Antimicrobial, Antioxidant properties, Hepatoprotective effects and Analysis of Bioactive Natural Compounds

In antibacterial screening performed by disc diffusion method against two gram negative bacteria namely Xanthomonas campestris (plant pathogen) and Aeromonas hydrophila (animal pathogen), it was found that the methanol extracts of all the plant samples showed significant activity against the two tested bacteria. [...]the need for potent antioxidants in our diet and drug supplements becomes very necessary 57-62 A study which utilises six pretreatment methods before cooking on the peroxidase activity, chlorophyll and antioxidant status of S. nigrum L., showed that pretreatment methods have significant effects (p < 0.05) on the parameters measured. The test drug significantly lowered the CCl4-induced elevation of hepatic enzyme markers (GOT, GPT, ALP, and total bilirubin) and decreased superoxide and hydroxyl radical generation. 6.Hypotensive potential Sn which has been used as an antipyretic and anticancer in folk medicine was investigated for its antihypertensive properties 78-90. A 150 kDa glycoprotein isolated from Sn is made up of carbohydrates (69.74%) and protein (30.26%), which contains more than 50% hydrophobic amino acids such as glycine and proline blocked nuclear factor-kappa B (NF-_B) activation, and reduced inducible nitric oxide (iNO) production in vitro at a concentration of 40 _g/ml. 7.