Intravenous Immune Globulin to Prevent Heparin-Induced Thrombocytopenia: Letter

Intravenous Immune Globulin to Prevent Heparin-Induced Thrombocytopenia: Letter

Anti-platelet factor 4-heparin antibodies present a major risk of heparin-induced thrombocytopenia (HIT). The use of intravenous immune globulin neutralized large amounts of these antibodies in a patient so that heparin could be used safely during emergency surgery.

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Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2018-05, Vol.378 (19), p.1845
Hauptverfasser: Warkentin, Theodore E, Climans, Troy H, Morin, Pierre-Aurèle
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Blood platelets
Catheters
Enzymes
Globulins
Heart surgery
Heparin
Immune response
Immunoglobulins
Informed consent
Intravenous administration
Platelet factor 4
Serotonin
Side effects
Surgery
Thrombocytopenia
Vascular surgery
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Beschreibung
Zusammenfassung:Anti-platelet factor 4-heparin antibodies present a major risk of heparin-induced thrombocytopenia (HIT). The use of intravenous immune globulin neutralized large amounts of these antibodies in a patient so that heparin could be used safely during emergency surgery.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1801799