Safety and efficacy of 68Ga-DOTATOC PET/CT in children and young adults

Safety and efficacy of 68Ga-DOTATOC PET/CT in children and young adults

Objectives: Determine the Safety, Sensitivity and Specificity of 68Ga-DOTATOC PET/CT in children and young adults with solid tumors. Methods: A series of three prospective, IRB approved, clinical trials evaluating safety and efficacy of 68Ga-DOTATOC PET/CT were conducted at the University of Iowa un...

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Veröffentlicht in:The Journal of nuclear medicine (1978) 2017-05, Vol.58, p.38
Hauptverfasser: Abongwa, Chenue, Bell, Sarah, McNeely, Parren, Schafer, Blanca, Abusin, Ghada, O'Dorisio, Thomas, Zamba, Gideon, Menda, Yusuf, O'Dorisio, M Sue
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Cancer
Children
Children & youth
Clinical trials
Effectiveness
Gallium
Medical imaging
Medical personnel
Medical research
Medulloblastoma
Meningioma
Neuroblastoma
Neuroendocrine tumors
Nuclear engineering
Nuclear medicine
Nuclear safety
Pheochromocytoma
Physicians
Positron emission
Positron emission tomography
Safety
Sensitivity
Solid tumors
Tomography
Tumors
Young adults
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Zusammenfassung:Objectives: Determine the Safety, Sensitivity and Specificity of 68Ga-DOTATOC PET/CT in children and young adults with solid tumors. Methods: A series of three prospective, IRB approved, clinical trials evaluating safety and efficacy of 68Ga-DOTATOC PET/CT were conducted at the University of Iowa under IND# 114,398 for subjects ages 6 months to 90 years. This study reports results for the 26 children and young adults, ages 16 months to 29 years who participated in these trials. DOTATOC was radiolabeled with gallium-68 at the University of Iowa PET Center. Activity injected was 0.043 mCi/kg with an upper limit of 3 mCi for subjects
ISSN:0161-5505
1535-5667