Transcription control by the ENL YEATS domain in acute leukemia

Recurrent chromosomal translocations involving the mixed lineage leukemia gene (MLL) give rise to highly aggressive acute leukemia associated with poor clinical outcomes. The preferential involvement of chromatin-associated factors in MLL rearrangements belies a dependency on transcriptional control...

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Veröffentlicht in:	European journal of cancer (1990) 2016-12, Vol.69, p.S85-S86
Hauptverfasser:	Erb, M, Winter, G, Dastjerdi, S, Scott, T, Sanjana, N, Shalem, O, Buckley, D, Zhang, F, Bradner, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin Chromosome translocations CRISPR Genes Genetics Genomes Hematology, Oncology and Palliative Medicine Leukemia Target recognition Transcription
Online-Zugang:	Volltext
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