乳腺Dynamic 造影MR 検査におけるtime-intensity-curve のGd-DTPA とGadobutrol 間での比較検討

The purpose of this study was to compare the time-intensity curve (TIC) on multiphase contrast-enhanced breast magnetic resonance imaging (MRI) between Gadobenatedimeglumine (Gd-DTPA) and Gadobutrol. We assessed the images of 53 cases obtained from MRI that had malignant findings by pathology from October 2015 to October 2016 in our institute. Gd-DTPA and Gadobutrol were administrated in 16 and 37 cases, respectively. The TIC of the lesion was classified according to the Kuhl’s method (type I: persistent pattern, type II: plateau pattern and type III: washout pattern). Type III was the most common TIC pattern in both the groups (Gd-DTPA, 12 cases; Gadobutrol, 18 cases). Type II was the second common TIC pattern in Gadobutrol group (12 cases). As a result, there was no significant difference in TIC analysis between Gd-DTPA and gadobutrol. In conclusion, the contrast between Gd-DTPA and Gadobutrol contrast media did not differ in TIC pattern of multiphasic contrast-enhanced breast MRI.