Non-classical hydrogen bond triggered strand displacement for analytical applications and DNA nanostructure assembly

Non-classical hydrogen bond triggered strand displacement for analytical applications and DNA nanostructure assembly

We demonstrated a new mode of strand displacement reaction by using cyanuric acid (CA) mediated poly(adenine) (poly(A)) assembly as a toehold, which is the first non-classical hydrogen bond triggered strand displacement. The reaction is even faster than Watson–Crick bond triggered strand displacemen...

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Veröffentlicht in:New journal of chemistry 2018, Vol.42 (9), p.6636-6639
Hauptverfasser: Han, Manli, Fan, Qingsheng, Zhang, Yi, Xu, Lida, Yu, Changyuan, Su, Xin
Format: Artikel
Sprache:eng
Schlagworte:
Assembly
Cyanuric acid
Deoxyribonucleic acid
Displacement
DNA
Hydrogen bonds
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Zusammenfassung:We demonstrated a new mode of strand displacement reaction by using cyanuric acid (CA) mediated poly(adenine) (poly(A)) assembly as a toehold, which is the first non-classical hydrogen bond triggered strand displacement. The reaction is even faster than Watson–Crick bond triggered strand displacement.
ISSN:1144-0546
1369-9261
DOI:10.1039/C7NJ05141G