PROTECTIVE EFFECT OF ASTAXANTHIN AGAINST ALUMINUM INDUCED LIVER OXIDATIVE DAMAGE

PROTECTIVE EFFECT OF ASTAXANTHIN AGAINST ALUMINUM INDUCED LIVER OXIDATIVE DAMAGE

In this study, protective effect of a potent antioxidant astaxanthine on preventing rat liver damage due to Al exposure was evaluated. In experimental design, 20 Wistar-albino rats were divided into four groups as Control, Aluminum (20 mg/kg/day i.p), Al + Astaxanthine (5 mg/kg/day AST orally, Al 20...

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Veröffentlicht in:Fresenius environmental bulletin 2017-10, p.6159
Hauptverfasser: Akkoyun, H Turan, Bengu, Aydin Sukru, Akkoyun, Mahire Bayramoglu, Ulucan, Aykut, Arihan, Okan
Format: Artikel
Sprache:eng
Schlagworte:
Aluminum
Antioxidants
Astaxanthin
Chloramphenicol O-acetyltransferase
Damage assessment
Damage prevention
Enzymatic activity
Enzyme activity
Enzymes
Experimental design
Liver
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Zusammenfassung:In this study, protective effect of a potent antioxidant astaxanthine on preventing rat liver damage due to Al exposure was evaluated. In experimental design, 20 Wistar-albino rats were divided into four groups as Control, Aluminum (20 mg/kg/day i.p), Al + Astaxanthine (5 mg/kg/day AST orally, Al 20 mg/kg/day i.p) and AST (5 mg/kg/day). Study was conducted for 14 days. GSH was found significantly low in Al group compared to control and significantly high in AST and AST + Al administered groups compared to Al group(p
ISSN:1018-4619
1610-2304