Isolation, Characterization, and Antimicrobial Activity of Extracellular Polypeptides from Diazotrophic Strain Rhizobium radiobacter

Isolation, Characterization, and Antimicrobial Activity of Extracellular Polypeptides from Diazotrophic Strain Rhizobium radiobacter

Antimicrobial polypeptide fractions were isolated from Rhizobium radiobacter culture medium and purified. Mass-spectrometric analysis showed that the most active biocidal peptide fraction contained 24 components with molecular masses in the range 1171.14–3626.78 Da. The isolated peptide fractions co...

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Veröffentlicht in:Chemistry of natural compounds 2018-03, Vol.54 (2), p.330-333
Hauptverfasser: Rozi, P., Rasulov, B. A., Waili, A., Mijiti, Y., Gao, Y. H., Yili, A., Aisa, H. A.
Format: Artikel
Sprache:eng
Schlagworte:
Antiinfectives and antibacterials
Antimicrobial agents
Biocides
Biopolymers
E coli
Escherichia coli
Herbal medicine
Medicinal plants
Medicine
Organic Chemistry
Peptides
Pharmacy
Plant Sciences
Polypeptides
Spectrometry
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Zusammenfassung:Antimicrobial polypeptide fractions were isolated from Rhizobium radiobacter culture medium and purified. Mass-spectrometric analysis showed that the most active biocidal peptide fraction contained 24 components with molecular masses in the range 1171.14–3626.78 Da. The isolated peptide fractions contained 60 and 56% protein, respectively, and inhibited the growth of test pathogens Candida albicans (CA) and Escherichia coli (EC). These polypeptides demonstrated protective properties.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-018-2334-y