A rare anatomical location of human papillomavirus-related penile warty carcinoma: Simultaneous axillary involvement

Excised tissue from both sites showed histopathologic features consistent with warty squamous cell carcinoma and human papillomavirus 16 (HPV16) was detected in all the specimens on polymerase chain reaction (PCR) and DNA analysis. According to the largest study of human papillomavirus infection in penile cancer by Rubin et al., only basaloid (80%) and warty (100%) types of penile squamous cell carcinomas were found to be consistently associated with human papillomavirus. Confusion on classification of verruciform tumors resulted in the poor recognition of the disease in earlier studies. [...]reporting of new cases of warty cell carcinomas is important.