3,4-Disubstituted maleimides: synthesis and biological activity

3,4-Disubstituted maleimides: synthesis and biological activity

This review is devoted to methods for the synthesis of 3,4-disubstituted maleimides – compounds that often show pronounced biological activity. We offer classification of synthetic methods, present comparative analysis of various approaches while describing their advantages and drawbacks. The areas...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2018-02, Vol.54 (2), p.103-113
Hauptverfasser: Panov, Alexey A., Simonov, Alexander Yu, Lavrenov, Sergey N., Lakatosh, Sergey A., Trenin, Alexey S.
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Antibiotics
Biological activity
Chemistry
Chemistry and Materials Science
Dyes
Organic Chemistry
Pharmacy
Protein kinases
Resveratrol
Reviews
Synthesis
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Beschreibung
Zusammenfassung:This review is devoted to methods for the synthesis of 3,4-disubstituted maleimides – compounds that often show pronounced biological activity. We offer classification of synthetic methods, present comparative analysis of various approaches while describing their advantages and drawbacks. The areas of practical applications are indicated for several 3,4-disubstituted maleimide derivatives in the role of pharmaceutical agents or reactive dyes. The majority of the considered publications are from the last 10 years.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-018-2240-z