Consequences of potassium dichromate intake on proteic profile in female rats, Rattus norvegicus (six months exposure)

The study carried out on 28 white Wistar adult female rats, divided in 3 experimental (E) groups, exposed for 6 months to 25ppmCr - LOAEL(E1), 50 ppm Cr (E2), 75 ppm Cr (E3) and one control (C) group - tap water, pointed out: significant decrease of total protein seric level below the bottom value of the physiologic limits, inversely correlated with the exposure level; significant decrease of albumin and globulin seric level, inversely correlated with the exposure level; significant increase of urea and creatinine seric level (each exceeding the maximum physiological limit), directly correlated with the exposure level.