Stenotrophomonas maltophilia : an emerging opportunist human pathogen
Summary Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen in the debilitated host. S maltophilia is not an inherently virulent pathogen, but its ability to colonise respiratory-tract epithelial cells and surfaces of medical devices makes it a ready coloniser of hospital...
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Veröffentlicht in: | The Lancet infectious diseases 2009-05, Vol.9 (5), p.312-323 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Summary Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen in the debilitated host. S maltophilia is not an inherently virulent pathogen, but its ability to colonise respiratory-tract epithelial cells and surfaces of medical devices makes it a ready coloniser of hospitalised patients. S maltophilia can cause blood-stream infections and pneumonia with considerable morbidity in immunosuppressed patients. Management of infection is hampered by high-level intrinsic resistance to many antibiotic classes and the increasing occurrence of acquired resistance to the first-line drug co-trimoxazole. Prevention of acquisition and infection depends upon the application of modern infection-control practices, with emphasis on the control of antibiotic use and environmental reservoirs. |
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ISSN: | 1473-3099 1474-4457 |
DOI: | 10.1016/S1473-3099(09)70083-0 |