COMPARISON OF HIGH SHEAR STRESS-INDUCED THROMBOTIC AND THROMBOLYTIC EFFECT BETWEEN ASPIRIN, CLOPIDOGREL AND VERY LOW DOSE RIVAROXABAN AND ASPIRIN, TICAGRELOR TREATMENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME

Background Global thrombosis test (GTT) is a simple but useful method to measure high shear stress-induced whole blood thrombotic and endogenous thrombolytic activity and it may mimic platelet aggregation in acute coronary syndrome (ACS) condition more accurately compared to conventional platelet function tests. Conclusion High shear stress-induced global thrombotic and lytic activity did not differ between the two antithrombotic regimens although TICA showed more potent inhibition of ADP-induced platelet aggregation.