Oligomerization of opioid receptors with beta2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation

Oligomerization of opioid receptors with beta2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation

G-protein-coupled receptors (GPCRs) have recently joined the list of cell surface receptors that dimerize. Dimerization has been shown to alter the ligand-binding, signaling, and trafficking properties of these receptors.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2001-01, Vol.98 (1), p.343
Hauptverfasser: Jordan, B A, Trapaidze, N, Gomes, I, Nivarthi, R, Devi, L A
Format: Artikel
Sprache:eng
Schlagworte:
Neurology
Pharmacology
Proteins
Stimulants
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:G-protein-coupled receptors (GPCRs) have recently joined the list of cell surface receptors that dimerize. Dimerization has been shown to alter the ligand-binding, signaling, and trafficking properties of these receptors.
ISSN:0027-8424
1091-6490