An Eph receptor regulated integrin activity through R-Ras

An Eph receptor regulated integrin activity through R-Ras

The ability of integrins to mediate cell attachment to extracellular matrices and to blood proteins is regulated from inside the cell. increased ligand-binding activity of integrins is critical for platelet aggregation upon blood clotting and for leukocyte extravasation to inflamed tissues.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1999-11, Vol.96 (24), p.13813
Hauptverfasser: Zou, June X, Wang, Bingcheng, Kalo, Matthew S, Zisch, Andreas H
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Proteins
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Beschreibung
Zusammenfassung:The ability of integrins to mediate cell attachment to extracellular matrices and to blood proteins is regulated from inside the cell. increased ligand-binding activity of integrins is critical for platelet aggregation upon blood clotting and for leukocyte extravasation to inflamed tissues.
ISSN:0027-8424
1091-6490