Chipping Away at Stem Cells

Chipping Away at Stem Cells

Chu and Gage discuss recent research which suggests that stem cells originating from different tissues may share a common genetic program responsible for maintaining them in an undifferentiated proliferative state. Once placed in a novel environment, the plastic nature of stem cells would allow them...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2001-07, Vol.98 (14), p.7652-7653
Hauptverfasser: Chu, Vi T., Gage, Fred H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Bone marrow
Cell Differentiation
Cell Lineage
Central nervous system
Commentaries
Complementary DNA
Genes
Genetics
Hematopoietic system
Humans
Medical research
Mice
Neural stem cells
Organ Specificity
Progenitor cells
Stem cell transplantation
Stem cells
Stem Cells - cytology
Stem Cells - physiology
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Beschreibung
Zusammenfassung:Chu and Gage discuss recent research which suggests that stem cells originating from different tissues may share a common genetic program responsible for maintaining them in an undifferentiated proliferative state. Once placed in a novel environment, the plastic nature of stem cells would allow them to respond to local cues and activate the appropriate differentiation pathway.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.141244198