Potassium-channel activation in response to low doses of (gamma)-irradition involves reactive oxygen intermediates in nonexcitatory cells

Potassium-channel activation in response to low doses of (gamma)-irradition involves reactive oxygen intermediates in nonexcitatory cells

Active oxygen species are generated during pathophysiologic conditions such as inflammation and ionizing radiation exposure. A hypothesis is tested claiming that an early cellular event in response to these species involves regulation of ion channels. The results are discussed.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1993-02, Vol.90 (3), p.908
Hauptverfasser: Kuo, Sophia S, Saad, Alie H, Koong, Albert C, Hahn, George M, Giaccia, Amato J
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
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Zusammenfassung:Active oxygen species are generated during pathophysiologic conditions such as inflammation and ionizing radiation exposure. A hypothesis is tested claiming that an early cellular event in response to these species involves regulation of ion channels. The results are discussed.
ISSN:0027-8424
1091-6490