The andenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization

Adenoviruses (Ads) have evolved multiple mechanisms to evade the host immune response. Several of the immunomodulatory Ad proteins are encoded in early transcription unit 3 (E3).

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1998-08, Vol.95 (17), p.10072
Hauptverfasser: Elsing, Andreas, Burgert, Hans-Gerhard
Format: Artikel
Sprache:eng
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Zusammenfassung:Adenoviruses (Ads) have evolved multiple mechanisms to evade the host immune response. Several of the immunomodulatory Ad proteins are encoded in early transcription unit 3 (E3).
ISSN:0027-8424
1091-6490