Vector-mediated delivery of 125I-labeled beta-amyloid peptide Abeta1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the Abeta1-40/vector complex

Vector-mediated delivery of 125I-labeled beta-amyloid peptide Abeta1-40 through the blood-brain barrier and binding to Alzheimer disease amyloid of the Abeta1-40/vector complex

Saito et al show that blood-brain barrier (BBB) transport and access to amyloid within the brain may be achieved by conjugation of Abeta1-40 to a vector-mediated BBB drug delivery system.

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1995-10, Vol.92 (22), p.10227
Hauptverfasser: Saito, Yasunari, Buciak, Jody, Yang, Jing, Pardridge, William M
Format: Artikel
Sprache:eng
Schlagworte:
Biology
Blood
Brain
Neurology
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Zusammenfassung:Saito et al show that blood-brain barrier (BBB) transport and access to amyloid within the brain may be achieved by conjugation of Abeta1-40 to a vector-mediated BBB drug delivery system.
ISSN:0027-8424
1091-6490