The interleukin (IL) 2 receptor (beta) chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

It is shown that the interleukin-T-mediated stimulation of cytokine-dependent T-cell line or the activation of large granular lymphocytes is not blocked by the addition of antibodies that bind specifically to interleukin-2 or to interleukin-2 receptor alpha yet is inhibited by the addition of Mik-be...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1994-05, Vol.91 (11), p.4940
Hauptverfasser: Bamford, Richard N, Grant, Angus J, Burton, Jack D, Peters, Christian
Format: Artikel
Sprache:eng
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Zusammenfassung:It is shown that the interleukin-T-mediated stimulation of cytokine-dependent T-cell line or the activation of large granular lymphocytes is not blocked by the addition of antibodies that bind specifically to interleukin-2 or to interleukin-2 receptor alpha yet is inhibited by the addition of Mik-beta1.
ISSN:0027-8424
1091-6490