Antigen-binding glycosylation inhibiting factor from a human T-cell hybridoma specific for bee venom phospholipase A(2)

Antigen-binding glycosylation inhibiting factor from a human T-cell hybridoma specific for bee venom phospholipase A(2)

Experiments were conducted to establish monoclonal antibodies specific for human antigen-binding glycosylation inhibiting factor (GIF) and to obtain biochemical evidence for the presence of antigen-specific human T-cell factors having affinity for nominal antigen. According to the results, the 13-kD...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1994-03, Vol.91 (7), p.2824
Hauptverfasser: Gomi, Hideho, Tagaya, Yutaka, Nakano, Tatsumi, Mikayama, Toshifumi, Ishizaka, Kimishige
Format: Artikel
Sprache:eng
Schlagworte:
Bees
Immunity (Disease)
Medical research
Poisons
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Zusammenfassung:Experiments were conducted to establish monoclonal antibodies specific for human antigen-binding glycosylation inhibiting factor (GIF) and to obtain biochemical evidence for the presence of antigen-specific human T-cell factors having affinity for nominal antigen. According to the results, the 13-kDa GIF is a subunit of the antigen-binding T-cell factor.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.91.7.2824