Detection of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development
The role of the T-cell receptor (TCR) beta gene transcriptional enhancer in intrathymic T-cell development was assessed in mouse strains in which the TCR beta enhancer was deleted. The effects of the deletion on lymphoid-cell differentiation, beta gene rearrangement and transcription are described.
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1996-07, Vol.93 (15), p.7877 |
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| container_issue | 15 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 93 |
| creator | Bouvier, Gaelle Watrin, Francoise Naspetti, Marianne Verthuy, Christophe |
| description | The role of the T-cell receptor (TCR) beta gene transcriptional enhancer in intrathymic T-cell development was assessed in mouse strains in which the TCR beta enhancer was deleted. The effects of the deletion on lymphoid-cell differentiation, beta gene rearrangement and transcription are described. |
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| fulltext | fulltext |
| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 1996-07, Vol.93 (15), p.7877 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_proquest_journals_201318389 |
| source | Jstor Complete Legacy; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Cells Genes Immunity (Disease) Rodents |
| title | Detection of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development |
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