Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates Cd8positive cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates Cd8positive cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

Research data suggest that cytokine-producing tumor cells are very potent stimulators of immunity against tumors within the central nervous system (CNS), but effector responses in the CNS may be different from those obtained against subcutaneous tumors.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1996-09, Vol.93 (19), p.10399
Hauptverfasser: Sampson, John H, Archer, Gerald E, Ashley, David M, Fuchs, Herbert E
Format: Artikel
Sprache:eng
Schlagworte:
Immunity (Disease)
Medical research
Nervous system
Tumors
Vaccines
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Zusammenfassung:Research data suggest that cytokine-producing tumor cells are very potent stimulators of immunity against tumors within the central nervous system (CNS), but effector responses in the CNS may be different from those obtained against subcutaneous tumors.
ISSN:0027-8424
1091-6490