Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: A possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated

Using a series of cyclosporin A, as well as FK506, analogs, including some devoid of calcineurin phosphatase inhibition activity, Renoir et al conclude that the potentiation effects of these drugs on Dex-induced chloramphenicol acetyltransferase (CAT) gene expression in LMCAT cells do not occur through a calcineurin-mediated pathway.