MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steriodogenesis

MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steriodogenesis

Mutations that inactivate the steroidogenic acute regulatory protein (StAR) were correlated with amino acid residues that are identical or similar among StAR and MLN64, indicating that conserved motifs are important for steroidogenic activity.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1997-08, Vol.94 (16), p.8462
Hauptverfasser: Watari, Hidemichi, Arakane, Futoshi, Moog-Lutz, Christel, Kallen, Caleb B
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Biochemistry
Cholesterol
Mutation
Proteins
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Zusammenfassung:Mutations that inactivate the steroidogenic acute regulatory protein (StAR) were correlated with amino acid residues that are identical or similar among StAR and MLN64, indicating that conserved motifs are important for steroidogenic activity.
ISSN:0027-8424
1091-6490