The peptide p2Ca is immunodominant in allorecognition of L(d) by (beta) chain variable region V(beta)8(positive) but not V(beta)8(negative) strains

The peptide p2Ca is immunodominant in allorecognition of L(d) by (beta) chain variable region V(beta)8(positive) but not V(beta)8(negative) strains

It is reported that ptwoCa is immunodominant in allorecognition of the murine major histocompatibility complex (MHC) I molecule H-2Ld in mice. Data indicate that peptide immunodominance can occur in allorecognition and that this immunodominance may be influenced by the available T-cell receptor repe...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1994-11, Vol.91 (24), p.11482
1. Verfasser: Connolly, Janet M
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Genetics
Immunity (Disease)
Rodents
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Zusammenfassung:It is reported that ptwoCa is immunodominant in allorecognition of the murine major histocompatibility complex (MHC) I molecule H-2Ld in mice. Data indicate that peptide immunodominance can occur in allorecognition and that this immunodominance may be influenced by the available T-cell receptor repertoire.
ISSN:0027-8424
1091-6490