Apc(Min), a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias

Apc(Min), a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias

ApcMin, multiple intestinal neoplasia, is a point mutation in the murine homolog of the APC gene. A study investigated whether the presence of ApcMin predisposes one to mammary carcinomas and focal alveolar hypoplasias.

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1993-10, Vol.90 (19), p.8977
Hauptverfasser: Moser, Amy Rapaich, Mattes, Ellen M, Dove, William F, Haag, Jill D
Format: Artikel
Sprache:eng
Schlagworte:
Breast cancer
Genetics
Medical research
Mutation
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Zusammenfassung:ApcMin, multiple intestinal neoplasia, is a point mutation in the murine homolog of the APC gene. A study investigated whether the presence of ApcMin predisposes one to mammary carcinomas and focal alveolar hypoplasias.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.90.19.8977