Mechanism of GTP hydrolysis by G-protein (alpha) subunits

Mechanism of GTP hydrolysis by G-protein (alpha) subunits

Hydrolysis of GTP by a variety of guanine nucleotide-binding proteins is a crucial step for regulation of these biological switches. A study used a conserved glutamic residue in the alpha subunit of G proteins to examine GTP hydrolysis.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1994-10, Vol.91 (21), p.9828
Hauptverfasser: Kleuss, Christiane, Raw, Andre S, Lee, Ethan, Sprang, Stephen R, Gilman, Alfred G
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Mutation
Proteins
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Hydrolysis of GTP by a variety of guanine nucleotide-binding proteins is a crucial step for regulation of these biological switches. A study used a conserved glutamic residue in the alpha subunit of G proteins to examine GTP hydrolysis.
ISSN:0027-8424
1091-6490