Can Functional Connectivity at Resting Brain in ADHD Indicate the Impairments in Sensory-Motor Functions and Face/Emotion Recognition?

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease known to cause impairments in cognitive, sensory-motor functions and face/emotion recognition. This study aimed to examine the resting-state brain networks in children with ADHD using functional magnetic resonance imaging. We performed seed-to-voxel and region of interest (ROI) analyses including all Broadmann areas (BAs) comprehensively. Thirty right-handed children aged between 9 and 16 years (15 with ADHD and 15 typically developing control subjects closely matched for age and gender) were included. Ninety five brain regions including 84 BAs and 11 Default Mode network (DMN)-related regions (rsREL) were studied using seed-based and ROI-to-ROI analysis and connectivity measures were calculated (p