RECA-DEPENDENT RECOVERY OF ARRESTED DNA REPLICATION FORKS

DNA damage encountered during the cellular process of chromosomal replication can disrupt the replication machinery and result in mutagenesis or lethality. The RecA protein of Escherichia coli is essential for survival in this situation: It maintains the integrity of the arrested replication fork an...

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Veröffentlicht in:	Annual review of genetics 2003-01, Vol.37 (1), p.611-646
Hauptverfasser:	Courcelle, Justin, Hanawalt, Philip C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell cycle Chromosomes Deoxyribonucleic acid DNA DNA Damage DNA repair DNA Repair - physiology DNA replication DNA Replication - physiology E coli Escherichia coli - genetics Escherichia coli - physiology Gene Expression Regulation, Bacterial - physiology Genomics Mutation Proteins Rec A Recombinases - metabolism RecA recombination repair replication
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