Evaluation of Neutrophil Lymphocyte Ratio, Tp-E Interval and Tp-E/QT Ratio in Subjects with Hypertension and Prehypertension

[...]the present study was designed to evaluate NLR, Tp-e interval and Tp-e/QT ratio subjects with hypertension and prehypertension.Study Design Between September 2012 and April 2013, the hypertensive, prehypertensive and normotensive healthy subjects who were admitted to our outpatient clinic were evaluated. According to inclusion and exclusion criteria the overall study population consisted of 95 subjects: 28 healthy volunteers with normal blood pressure (BP) (group I), 35 subjects with prehypertension (group II), and 32 patients with new onset hypertension (group III). Hypertension (n=32) Age (years) 44.8±10.8 44.1±12.5 47.6±9.9 Males / Females 10/18 13/22 13/19 BMI (kg/m2) 28.6±3.2 29.1±4.9 29.2±4.1 Systolic BP (mmHg) 115.9±7.8 134.6±16.5 * 160.8±19.3 * # Diastolic BP (mmHg) 71.2±6.9 81.4±9.1 * 94.2±8.2 * # Heart rate (beats/min) 75.3±11.1 78.9±12.4 79.5±12.3 LV EDD (mm) 46.3±3.4 47.1±3.7 48.2±3.0 LV EF (%) 66.2±2.8 66.5±2.8 65.9±2.6 LA dimension (mm) 33.9±3.5 33.8±3.4 36.5±3.1 ¥ Fasting glucose (mg/dl) 90.9±6.4 93.4±6.8 94.5±8.3 Creatinine (mg/dl) 0.76±0.12 0.77±0.19 0.79±0.19 Hemoglobin (g/dl) 13.8±1.0 13.8±1.6 14.1±1.5 WBC (K/uL) 7.2±1.3 7.7±1.8 7.3±1.5 Neutrophils (K/uL) 2.0±0.8 2.1±0.8 2.2±0.9 Lymphocytes (K/uL) 2.2±0.5 2.3±0.5 2.1±0.6 N/L ratio 2.04±0.8 2.08±0.8 2.18±0.9 Mean platelet volume (fL) 8.0±0.61 8.3±0.77 8.1±0.70 CRP (mg/l) 4.2±1.4 4.0±1.3 3.9±1.1 cQTd (ms) 34.3±11.0 33.4±9.1 47.8±16.2 * # cTp-e (ms) 95.6±14.3 98.0±11.6 107.0±10.7 @ $ Tp-e/QT 0.22±0.03 0.22±0.03 0.25±0.03 & ^ Table 1 Demographic, laboratory, and electrocardiographic characteristics of the study groups