Immunological changes induced by Pru p 3-glycodendrimers
Rationale Glycodendrimers functionalized with mannose are promising structures to enhance allergen interaction with antigen presenting cells via C-type lectin receptors and modulate the immune response. Responses were analysed in peach allergic patients and healthy controls, by studying monocyte-der...
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| Veröffentlicht in: | Journal of allergy and clinical immunology 2018-02, Vol.141 (2), p.AB124-AB124 |
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| container_end_page | AB124 |
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| container_issue | 2 |
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| container_title | Journal of allergy and clinical immunology |
| container_volume | 141 |
| creator | Palomares, Maria Francisca Gomez, Francisca Mascaraque, Ainhoa Bogas, Gador Ramos-Soriano, Javier Rodríguez, Maria José Torres Jaén, Maria Jose Rojo, Javier Mayorga, Cristobalina |
| description | Rationale Glycodendrimers functionalized with mannose are promising structures to enhance allergen interaction with antigen presenting cells via C-type lectin receptors and modulate the immune response. Responses were analysed in peach allergic patients and healthy controls, by studying monocyte-derived-dendritic cell (moDC) maturation and interaction using blocking DC-Sign (αCD209) and mannose (αCD206) receptors, and lymphocyte proliferation, by flow cytometry. |
| doi_str_mv | 10.1016/j.jaci.2017.12.394 |
| format | Article |
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| identifier | ISSN: 0091-6749 |
| ispartof | Journal of allergy and clinical immunology, 2018-02, Vol.141 (2), p.AB124-AB124 |
| issn | 0091-6749 1097-6825 |
| language | eng |
| recordid | cdi_proquest_journals_2007522896 |
| source | Elsevier ScienceDirect Journals |
| subjects | Antigen-presenting cells Cell growth Dendritic cells Food allergies Immunology Monocytes |
| title | Immunological changes induced by Pru p 3-glycodendrimers |
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