Effect of Host Genetic Background on Development of Autoimmunity in Transplanted and Vertically Transmitted Human Microbiota Mouse Models

Effect of Host Genetic Background on Development of Autoimmunity in Transplanted and Vertically Transmitted Human Microbiota Mouse Models

Results Community compositions of the Humicrobiota and Convmicrobiota were completely distinct in both mouse strains; C. jejuni infection did not alter community structure of either microbiota in either mouse strain. Both C57BL/6 and NOD Humicrobiotas exhibited large increases in the genus Bacteroid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2018-02, Vol.141 (2), p.AB184-AB184
Hauptverfasser: Mansfield, Linda S., Ethridge, Alexander D., Brooks, Phillip T., Brakel, Kelsey A., Bell, Julia A.
Format: Artikel
Sprache:eng
Schlagworte:
Animal models
Autoimmunity
Bacteroides
Bacteroidetes
Campylobacter
Campylobacter jejuni
Firmicutes
Infections
Microbiota
Pathogens
Rodents
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Results Community compositions of the Humicrobiota and Convmicrobiota were completely distinct in both mouse strains; C. jejuni infection did not alter community structure of either microbiota in either mouse strain. Both C57BL/6 and NOD Humicrobiotas exhibited large increases in the genus Bacteroides compared to their respective Convmicrobiotas; Bacteroides spp. can provide energy sources preferred by C. jejuni.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2017.12.585