Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation
Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. Results In healthy controls, there was a dramatic age-related decrease of serous submuco...
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Veröffentlicht in: | Journal of allergy and clinical immunology 2018-02, Vol.141 (2), p.AB203-AB203 |
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container_title | Journal of allergy and clinical immunology |
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creator | Jo, Ara Casale, Thomas B. Suh, Lydia A. Carter, Roderick G. Conley, David B. Kern, Robert C. Tan, Bruce K. Peters, Anju T. Grammer, Leslie C. Schleimer, Robert P. Cho, Seong Ho |
description | Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. Results In healthy controls, there was a dramatic age-related decrease of serous submucosal glandular cells and a relative increase of PAS-stained mucous cells, together with submucosal glandular metaplasia. |
doi_str_mv | 10.1016/j.jaci.2017.12.642 |
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Results In healthy controls, there was a dramatic age-related decrease of serous submucosal glandular cells and a relative increase of PAS-stained mucous cells, together with submucosal glandular metaplasia.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2017.12.642</identifier><language>eng</language><publisher>St. Louis: Elsevier Inc</publisher><subject>Age ; Mitochondria ; Oxidative stress</subject><ispartof>Journal of allergy and clinical immunology, 2018-02, Vol.141 (2), p.AB203-AB203</ispartof><rights>2017</rights><rights>Copyright Elsevier Science Ltd. Feb 1, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaci.2017.12.642$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids></links><search><creatorcontrib>Jo, Ara</creatorcontrib><creatorcontrib>Casale, Thomas B.</creatorcontrib><creatorcontrib>Suh, Lydia A.</creatorcontrib><creatorcontrib>Carter, Roderick G.</creatorcontrib><creatorcontrib>Conley, David B.</creatorcontrib><creatorcontrib>Kern, Robert C.</creatorcontrib><creatorcontrib>Tan, Bruce K.</creatorcontrib><creatorcontrib>Peters, Anju T.</creatorcontrib><creatorcontrib>Grammer, Leslie C.</creatorcontrib><creatorcontrib>Schleimer, Robert P.</creatorcontrib><creatorcontrib>Cho, Seong Ho</creatorcontrib><title>Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation</title><title>Journal of allergy and clinical immunology</title><description>Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. Results In healthy controls, there was a dramatic age-related decrease of serous submucosal glandular cells and a relative increase of PAS-stained mucous cells, together with submucosal glandular metaplasia.</description><subject>Age</subject><subject>Mitochondria</subject><subject>Oxidative stress</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kEtPwzAQhC0EEqXwBzhZ4pzgV5xY4hIhKEhAEQ9xtIy9AUdpXOy0ov-elHLmtNrVzOzoQ-iUkpwSKs_bvDXW54zQMqcsl4LtoQklqsxkxYp9NCFE0UyWQh2io5RaMu68UhPU3fsh2M_Qu-hNh-ff3pnBrwE_DxFSwrcJ1ykF680ADr_54RPXH5A9Qfd7mHWmd6vORPwEi-Cg8_0HrnuHH0wa4x5Dt1ni6xAXY2joj9FBY7oEJ39zil6vr14ub7K7-ez2sr7LLGVCZNQRYFQIzgWXhlSgpCsApBOqZIqRglvOWQNVpUTTSO6EY9JaZYC-N6V451N0tstdxvC1gjToNqxiP77UjJCyYFRRMarYTmVjSClCo5fRL0zcaEr0lqpu9Zaq3lLVlOmR6mi62Jlg7L_2EHWyHnoLzkewg3bB_2f_AV-ggD8</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Jo, Ara</creator><creator>Casale, Thomas B.</creator><creator>Suh, Lydia A.</creator><creator>Carter, Roderick G.</creator><creator>Conley, David B.</creator><creator>Kern, Robert C.</creator><creator>Tan, Bruce K.</creator><creator>Peters, Anju T.</creator><creator>Grammer, Leslie C.</creator><creator>Schleimer, Robert P.</creator><creator>Cho, Seong Ho</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>201802</creationdate><title>Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation</title><author>Jo, Ara ; Casale, Thomas B. ; Suh, Lydia A. ; Carter, Roderick G. ; Conley, David B. ; Kern, Robert C. ; Tan, Bruce K. ; Peters, Anju T. ; Grammer, Leslie C. ; Schleimer, Robert P. ; Cho, Seong Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1244-1d0e214433436a08e96d5ee6d497292053c332fe8894ff63d4d26cc9ae1bf74b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Age</topic><topic>Mitochondria</topic><topic>Oxidative stress</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jo, Ara</creatorcontrib><creatorcontrib>Casale, Thomas B.</creatorcontrib><creatorcontrib>Suh, Lydia A.</creatorcontrib><creatorcontrib>Carter, Roderick G.</creatorcontrib><creatorcontrib>Conley, David B.</creatorcontrib><creatorcontrib>Kern, Robert C.</creatorcontrib><creatorcontrib>Tan, Bruce K.</creatorcontrib><creatorcontrib>Peters, Anju T.</creatorcontrib><creatorcontrib>Grammer, Leslie C.</creatorcontrib><creatorcontrib>Schleimer, Robert P.</creatorcontrib><creatorcontrib>Cho, Seong Ho</creatorcontrib><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jo, Ara</au><au>Casale, Thomas B.</au><au>Suh, Lydia A.</au><au>Carter, Roderick G.</au><au>Conley, David B.</au><au>Kern, Robert C.</au><au>Tan, Bruce K.</au><au>Peters, Anju T.</au><au>Grammer, Leslie C.</au><au>Schleimer, Robert P.</au><au>Cho, Seong Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><date>2018-02</date><risdate>2018</risdate><volume>141</volume><issue>2</issue><spage>AB203</spage><epage>AB203</epage><pages>AB203-AB203</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. 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title | Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation |
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