Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation

Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. Results In healthy controls, there was a dramatic age-related decrease of serous submuco...

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Veröffentlicht in:Journal of allergy and clinical immunology 2018-02, Vol.141 (2), p.AB203-AB203
Hauptverfasser: Jo, Ara, Casale, Thomas B., Suh, Lydia A., Carter, Roderick G., Conley, David B., Kern, Robert C., Tan, Bruce K., Peters, Anju T., Grammer, Leslie C., Schleimer, Robert P., Cho, Seong Ho
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container_end_page AB203
container_issue 2
container_start_page AB203
container_title Journal of allergy and clinical immunology
container_volume 141
creator Jo, Ara
Casale, Thomas B.
Suh, Lydia A.
Carter, Roderick G.
Conley, David B.
Kern, Robert C.
Tan, Bruce K.
Peters, Anju T.
Grammer, Leslie C.
Schleimer, Robert P.
Cho, Seong Ho
description Methods NP and uncinate process tissues from young (18-49), mature (50-64), and older (>=65) adults with NP and age-matched healthy controls were examined with H&E and periodic acid-Schiff (PAS) staining. Results In healthy controls, there was a dramatic age-related decrease of serous submucosal glandular cells and a relative increase of PAS-stained mucous cells, together with submucosal glandular metaplasia.
doi_str_mv 10.1016/j.jaci.2017.12.642
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subjects Age
Mitochondria
Oxidative stress
title Mitochondrial Oxidative Stress Is Associated With Age-Related Glandular Remodeling And Nasal Polyp Formation
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