Phthalides and Other Metabolites from Roots of Ligusticum wallichii
A new phthalide that was identified using NMR and mass spectral data as (±)-3-methoxysedanenolide ( 1 ) and the nine known compounds sedanenolide ( 2 ), Z-ligustilide ( 3 ), Z-butylidenephthalide ( 4 ), methyl ferulate ( 5 ), trans-ferulic ( 6 ) and trans-isoferulic acids ( 7 ), falcarindiol ( 8 ),...
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| Veröffentlicht in: | Chemistry of natural compounds 2018, Vol.54 (1), p.34-37 |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A new phthalide that was identified using NMR and mass spectral data as (±)-3-methoxysedanenolide (
1
) and the nine known compounds sedanenolide (
2
), Z-ligustilide (
3
), Z-butylidenephthalide (
4
), methyl ferulate (
5
), trans-ferulic (
6
) and trans-isoferulic acids (
7
), falcarindiol (
8
), β-sitosterol (
9
), and daucosterol (
10
) were isolated from the MeOH extract of roots of Ligusticum wallichii. Compounds
7
and
8
exhibited high inhibitory activity against NO formation in RAW264.7 cells. |
|---|---|
| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-018-2253-y |