Comparison of the Effects of Epidural 0.5% Bupivacaine and 0.5% Levobupivacaine Administration Without Adjuvant Medication on Anaesthasia Quality, Side Effect Incidence and Analgesia Requirement Times in in Electively Operated Cases on Hip and Lower Extremity

Statistically no significant difference was found between the groups in terms of the onset and regression times of the sensory and motor blockade, time to reach dermatomes, initial analgesic requirement time, resolution time of the motor block, patient and surgeon satisfaction, heart rate (HR), noni...

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Veröffentlicht in:JK science : journal of medical education and research 2017-01, Vol.19 (1), p.53-58
Hauptverfasser: Kalsotra, Sanjay, Chowadhary, Jasmeen, Dogra, Sandeepika, Gulati, Samriti
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Sprache:eng
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Zusammenfassung:Statistically no significant difference was found between the groups in terms of the onset and regression times of the sensory and motor blockade, time to reach dermatomes, initial analgesic requirement time, resolution time of the motor block, patient and surgeon satisfaction, heart rate (HR), noninvasive systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP) and peripheral oxygen saturation (SpO2) values (P > 0.05). levobupivacaine could be a good alternative to bupivacaine in the patients whom we administered epidural anesthesia in elective hip and lower extremity surgeries, in terms of hemodynamic parameters, quality of anesthesia and analgesia, patient and surgeon satisfaction and complications. Systolic, diastolic and mean blood pressures (SBP, DBP, MBP), heart rate (HR) were monitored and peripheral oxygen saturation (SpO2) was measured with pulse oximetry in all the cases taken to the operating room. Important cause of cardiovascular side effects is that bupivacaine leave sodium channels slowly. [...]local anesthetics with similar action to bupivacaine, but fewer effects on cardiovascular system is needed for regional anesthesia. Levobupivacaine also decreases the cardiovascular and central nervous system toxicity to some extent (p value insignificant) which makes levobupivacaine an interesting alternative to bupivacaine. [...]it can be used with equal efficacy and slightly better safety than as bupivacaine in similar dose when injected epidurally.
ISSN:0972-1177