Reactions of 2-(trifluoroacetyl)chromones with aromatic amines

Reactions of 2-(trifluoroacetyl)chromones with aromatic amines

Aromatic amines reacted with 2-(trifluoroacetyl)chromones as С- or N-nucleophiles, depending on the conditions. When the reaction was performed under solvent-free conditions at 100°С for 12–18 h, they acted as С-nucleophiles and gave bishetarylcarbinols in 21–67% yields, while in refluxing toluene t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2017-12, Vol.53 (12), p.1362-1364
Hauptverfasser: Safrygin, Alexander V., Vetyugova, Darya A., Irgashev, Roman A., Sosnovskikh, Vyacheslav Ya
Format: Artikel
Sprache:eng
Schlagworte:
Amines
Aromatic amines
Chemistry
Chemistry and Materials Science
Nucleophiles
Organic Chemistry
Organic compounds
Pharmacy
Refluxing
Short Communications
Toluene
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Aromatic amines reacted with 2-(trifluoroacetyl)chromones as С- or N-nucleophiles, depending on the conditions. When the reaction was performed under solvent-free conditions at 100°С for 12–18 h, they acted as С-nucleophiles and gave bishetarylcarbinols in 21–67% yields, while in refluxing toluene the addition of primary arylamines occurred via the amino group, providing the corresponding hemiaminals (80–86%).
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-018-2218-x