Front Cover: Directed ortho‐Metalation of O‐Aryl N,N‐Dialkylcarbamates: Methodology, Anionic ortho‐Fries Rearrangement, and Lateral Metalation (Eur. J. Org. Chem. 4/2018)

The Front Cover shows a wheel centered on the aryl ortho‐lithiated O‐carbamate represented by the maple leaf (imagine a benzene ring) and by two ethyl hockey‐stick groups (both symbolic to Canada), the carbamate's partial history, its anionic equivalency to the venerable Fries rearrangement, an...

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Veröffentlicht in:European journal of organic chemistry 2018-01, Vol.2018 (4), p.423-423
Hauptverfasser: Miah, M. A. Jalil, Sibi, Mukund P., Chattopadhyay, S., Familoni, Oluwole B., Snieckus, Victor
Format: Artikel
Sprache:eng
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Zusammenfassung:The Front Cover shows a wheel centered on the aryl ortho‐lithiated O‐carbamate represented by the maple leaf (imagine a benzene ring) and by two ethyl hockey‐stick groups (both symbolic to Canada), the carbamate's partial history, its anionic equivalency to the venerable Fries rearrangement, and its rich chemistry. Follow the wheel from 12 o'clock in an R configuration passing through a carbamate used for treatment of a neuromuscular disease, through Karl Fries, and ending in directed ortho‐metalation (DoM), anionic ortho‐Fries rearrangement (AoF), and walking‐around‐the‐ring DoM – all very useful reactions for synthetic aromatic chemistry. More information can be found in the Full Papers (ejoc.201701142 and ejoc.201701143) by M. A. J. Miah, V. Snieckus et al.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201800016