Clinical picture

At surgery, the mass was localised with intraoperative ultrasound. The aortic adventia was indurated and erythematous at the site of attachment. The mass measured 2 cm by 5 cm and originated from a shallow intimal ulcer. The mass consisted of organising thrombus, and the aortic wall demonstrated acu...

Ausführliche Beschreibung

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Veröffentlicht in:The Lancet (British edition) 2003-05, Vol.361 (9370), p.1676
Hauptverfasser: Humbert, Vernon H, Tuna, Ishik C, Harrison, Michael R, Curtis, David B, Webster, Stevan A
Format: Artikel
Sprache:eng
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Beschreibung
Zusammenfassung:At surgery, the mass was localised with intraoperative ultrasound. The aortic adventia was indurated and erythematous at the site of attachment. The mass measured 2 cm by 5 cm and originated from a shallow intimal ulcer. The mass consisted of organising thrombus, and the aortic wall demonstrated acute and chronic inflammation with micro-thrombi in small blood vessels. A strongly positive IgG and IgA anti-cardiolipin antibody assay and a moderately positive IgM assay were subsequently identified, and the diagnosis of anti-phospholipid syndrome made. With acute arterial embolisation, transthoracic echocardiography is commonly used to identify a source, and to plan treatment (anti-coagulant therapy).
ISSN:0140-6736
1474-547X