Evidence for novel non-angiogenic pathway in breast-cancer metastasis

We have reported that angiogenic primary breast carcinoma can relapse not only as angiogenic, but also as non-angiogenic, lung metastases. This non-angiogenic pathway seems to be a novel pathway of cancer progression, and such tumours are likely to be resistant to antiangiogenic treatment.

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Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 2000-05, Vol.355 (9217), p.1787-1788
1. Verfasser:	Breast Cancer Progression Working Party
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast cancer Genital system. Mammary gland Investigative techniques, diagnostic techniques (general aspects) Medical research Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	We have reported that angiogenic primary breast carcinoma can relapse not only as angiogenic, but also as non-angiogenic, lung metastases. This non-angiogenic pathway seems to be a novel pathway of cancer progression, and such tumours are likely to be resistant to antiangiogenic treatment.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(00)02268-6