EFFECT OF PSYCHOSOCIAL TREATMENT ON SURVIVAL OF PATIENTS WITH METASTATIC BREAST CANCER

EFFECT OF PSYCHOSOCIAL TREATMENT ON SURVIVAL OF PATIENTS WITH METASTATIC BREAST CANCER

The effect of psychosocial intervention on time of survival of 86 patients with metastatic breast cancer was studied prospectively. The 1 year intervention consisted of weekly supportive group therapy with self-hypnosis for pain. Both the treatment (n = 50) and control groups (n = 36) had routine on...

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Veröffentlicht in:The Lancet (British edition) 1989-10, Vol.334 (8668), p.888-891
Hauptverfasser: Spiegel, David, Kraemer, HelenaC, Bloom, JoanR, Gottheil, Ellen
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Breast cancer
Breasts
Cancer
Death & dying
Gynecology. Andrology. Obstetrics
Intervention
Mammary gland diseases
Medical research
Medical sciences
Psychology
Survival
Tumors
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Zusammenfassung:The effect of psychosocial intervention on time of survival of 86 patients with metastatic breast cancer was studied prospectively. The 1 year intervention consisted of weekly supportive group therapy with self-hypnosis for pain. Both the treatment (n = 50) and control groups (n = 36) had routine oncological care. At 10 year follow-up, only 3 of the patients were alive, and death records were obtained for the other 83. Survival from time of randomisation and onset of intervention was a mean 36·6 (SD 37·6) months in the intervention group compared with 18·9 (10·8) months in the control group, a significant difference. Survival plots indicated that divergence in survival began at 20 months after entry, or 8 months after intervention ended.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(89)91551-1