INFANT FEEDING AND CHILDHOOD CANCER

A case-control study was used to assess whether inadequate exposure to the immunological benefits of human milk may affect infants' response to infection and make them more susceptible to childhood malignancies. 201 Denver children with cancer diagnosed at 1·5-15 years of age were compared with...

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Veröffentlicht in:The Lancet (British edition) 1988-08, Vol.332 (8607), p.365-368
Hauptverfasser: Davis, MargarettK, Savitz, DavidA, Graubard, BarryI
Format: Artikel
Sprache:eng
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Zusammenfassung:A case-control study was used to assess whether inadequate exposure to the immunological benefits of human milk may affect infants' response to infection and make them more susceptible to childhood malignancies. 201 Denver children with cancer diagnosed at 1·5-15 years of age were compared with 181 controls, who were selected to be similar to cases for age, sex, and area of residence. Infant feeding categories were: breast feeding (BF) >6 months; BF 6 months; and artificial feeding (AF, or exclusive non-human milk feeding). Compared with BF >6 months, a raised risk for total cancers was found in both BF 6 month and AF groups. This increased risk was largely due to an increased incidence of lymphoma (n = 26).
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(88)92835-8